Long QT syndrome. New electrocardiographic characteristics.
نویسندگان
چکیده
منابع مشابه
Long QT syndrome. New electrocardiographic characteristics.
The long QT syndrome is electrocardiographically characterized by a prolonged QT interval and by several other, more subtle, ST-T-U wave abnormalities, most of which have not been quantified. To determine the possible usefulness of several new electrocardiographic characteristics in identifying patients with known long QT syndrome, logistic regression models were applied to a data base of seven...
متن کاملElectrocardiographic risk stratification in families with congenital long QT syndrome.
AIMS The QT interval in the surface ECG is one of the most often used risk stratifiers in families with congenital long QT syndrome (LQTS). The best ECG lead for clinical management of LQTS families remains unclear. METHODS AND RESULTS The predictive power of the QTc interval in all ECG leads was studied in 200 consecutive genotyped LQTS family members to identify mutation carriers (n = 103; ...
متن کامل[New insights into the long-QT syndrome].
Long QT Syndrome (LQTS) is an arrhythmogenic disease in which prolongation of cardiac repolarization alters electrical stability of the heart predisposing affected individuals to cardiac arrest. The first arrhythmic manifestations occur during adolescence and largely are triggered by increased sympathetic activity. Mutations in genes encoding ion channels or ion channels’ controlling proteins h...
متن کاملDefining candidate drug characteristics for Long-QT (LQT3) syndrome.
Mutations of the SCN5A gene can significantly alter the function of cardiac myocyte sodium channels leading to increased risk of ventricular arrhythmia. Over the past decade, detailed Markov models of the action potential of cardiac cells have been developed. In such models, the effects of a drug can be treated as alterations in on- and off rates between open and inactivated states on one hand,...
متن کامل[Clinical and genetic characteristics of long QT syndrome].
Long QT syndrome (LQTS) is an arrhythmogenic ion channel disorder characterized by severely abnormal ventricular repolarization, which results in prolongation of the electrocardiographic QT interval. The condition is associated with sudden cardiac death due to malignant ventricular arrhythmias similar in form to the hallmark torsade de pointes. Eleven years after the identification of the princ...
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ژورنال
عنوان ژورنال: Circulation
سال: 1990
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.82.2.521